Question: "Is there proof for the inspiration of the Bible?"
Answer: Here are some evidences that the Bible is inspired (God-breathed), as declared in 2 Timothy 3:16:
1) Fulfilled prophecy. God spoke to men telling them of things He would bring about in the future. Some of them have already occurred. Others have not. For example, the Old Testament contains more than 300 prophecies concerning Jesus Christ's first coming. There is no doubt that these are prophecies from God because of manuscripts dated from before the birth of Christ. These were not written after the fact but beforehand.
2) The unity of Scripture. The Bible was written by approximately 40 human authors over a period of approximately 1,600 years. These men were quite diverse. Moses, was a political leader; Joshua, a military leader; David, a shepherd; Solomon, a king; Amos, a herdsman and fruit picker; Daniel, a prime minister; Matthew, a tax collector; Luke, a medical doctor; Paul, a rabbi; and Peter, a fisherman; among others. The Bible was also written under a variety of circumstances. It was written on 3 different continents, Europe, Asia, and Africa. Yet, the great themes of Scripture are maintained in all the writings. The Bible does not contradict itself. There is no way, apart from God the Holy Spirit supervising the writing of the Bible, that this could have been accomplished.
Contrast this with the Islamic Qur’an. It was compiled by one individual, Zaid bin Thabit, under the guidance of Mohammed's father-in-law, Abu-Bekr. Then, in A.D. 650, a group of Arab scholars produced a unified version and destroyed all variant copies to preserve the unity of the Qur’an. The Bible was unified from the time of its writing. The Qur’an had unity forced upon it by human editors.
3) The Bible presents its heroes truthfully with all of their faults and weaknesses. It does not glorify men as other religions do their heroes. Reading the Bible, one realizes that the people it describes have problems and do wrong just as we do. What made the heroes of the Bible great was that they trusted in God. One example is David, who is described as “a man after God's own heart” (1 Samuel 13:14). Yet, David committed adultery (2 Samuel 11:1-5) and murder (2 Samuel 11:14-26). This information could have easily been omitted from Scripture, but the God of truth included it.
4) Archaeological findings support the history recorded in Scripture. Though many unbelievers throughout history have tried to find archaeological evidence to disprove what is recorded in the Bible, they have failed. It is easy to say that Scripture is untrue. Proving it to be untrue is another matter. In fact, it has not been done. In the past, every time the Bible contradicted a current “scientific” theory, the Bible was proven later to be true and the scientific theory wrong. A good example is Isaiah 40:22. All the while that science declared the earth to be flat, the Bible stated that God “sits on the circle [sphere] of the earth.”
The Bible’s claims of being from God should not be understood as circular reasoning. The testimony of reliable witnesses—particularly Jesus, but also Moses, Joshua, David, Daniel, and Nehemiah in the Old Testament, and John and Paul in the New Testament—affirms the authority and verbal inspiration of the Holy Scriptures. Consider the following passages: Exodus 14:1; 20:1; Leviticus 4:1; Numbers 4:1;Deuteronomy 4:2; 32:48; Isaiah 1:10, 24; Jeremiah 1:11; Jeremiah 11:1–3; Ezekiel 1:3; 1 Corinthians 14:37; 1 Thessalonians 2:13; 2 Peter 1:16–21; 1 John 4:6.
Also of interest are the writings of Titus Flavius Josephus, a Jewish historian who wrote during the first century A.D. Josephus records some events which coincide with Scripture. Considering the evidence given, we wholeheartedly accept the Bible as being from God (2 Timothy 3:16).